NS5A-derived peptide C5A
General Information
DRACP ID DRACP03471
Peptide Name NS5A-derived peptide C5A
Sequence SWLRDIWDWICEVLSDFK
Sequence Length 18
UniProt ID P26664
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C109H155N25O29S
Absent amino acids AGHMNPQTY
Common amino acids DW
Mass 261506
Pl 4.06
Basic residues 2
Acidic residues 4
Hydrophobic residues 9
Net charge -2
Boman Index -2527
Hydrophobicity -3.33
Aliphatic Index 102.78
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 16500
Absorbance 280nm 970.59
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18287023
Title A Virocidal Amphipathic {Alpha}-Helical Peptide That Inhibits Hepatitis C Virus Infection in Vitro
Doi Not available
Year 2008
Literature 2
Pubmed ID 21801309
Title Rational design of peptides with anti-HCV/HIV activities and enhanced specificity
Doi Not available
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 4631