NS5A-derived peptide C5A

General Information


DRACP ID  DRACP03471

Peptide Name   NS5A-derived peptide C5A

Sequence  SWLRDIWDWICEVLSDFK

Sequence Length  18

UniProt ID  P26664 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antiviral



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03471

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C109H155N25O29S

Absent amino acids  AGHMNPQTY

Common amino acids  DW

Mass  261506

Pl  4.06

Basic residues  2

Acidic residues  4

Hydrophobic residues  9

Net charge  -2

Boman Index  -2527

Hydrophobicity  -3.33

Aliphatic Index  102.78

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  16500

Absorbance 280nm  970.59

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18287023

Title  A Virocidal Amphipathic {Alpha}-Helical Peptide That Inhibits Hepatitis C Virus Infection in Vitro

Doi Not available

Year  2008

Literature 2

Pubmed ID 21801309

Title  Rational design of peptides with anti-HCV/HIV activities and enhanced specificity

Doi Not available

Year  2011

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  4631

DRACP is developed by Dr.Zheng's team.