Peptide P [K7,14,22k; A12,20L]

General Information


DRACP ID  DRACP03475

Peptide Name   Peptide P [K7,14,22k; A12,20L]

Sequence  KWKSFLkTFKSLKkTVLHTLLkAISS

Sequence Length  26

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C127H200N30O28

Absent amino acids  CDEGMNPQRY

Common amino acids  L

Mass  304126

Pl  11.28

Basic residues  5

Acidic residues  0

Hydrophobic residues  11

Net charge  5

Boman Index  -451

Hydrophobicity  38.85

Aliphatic Index  105

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  220

Polar residues  7

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24805306

Title  Role of helicity of ?-helical antimicrobial peptides to improve specificity

Doi Not available

Year  2014

Literature 2

Pubmed ID 22837667

Title  Role of helicity on the anticancer mechanism of action of cationic-helical peptides

Doi Not available

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  4712

DRACP is developed by Dr.Zheng's team.