This work is licensed under a Creative Commons Attribution 4.0 International License.
Leucrocin I
General Information
DRACP ID DRACP03476
Peptide Name Leucrocin I
Sequence NGVQPKY
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C36H56N10O11
Absent amino acids ACDEFHILMRSTW
Common amino acids GKNPQVY
Mass 91210
Pl 9.3
Basic residues 1
Acidic residues 0
Hydrophobic residues 1
Net charge 1
Boman Index -1289
Hydrophobicity -142.86
Aliphatic Index 41.43
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 248.33
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24192554
Title Design and synthesis of cationic antibacterial peptide based on Leucrocin I sequence, antibacterial peptide from crocodile (Crocodylus siamensis) white blood cell extracts
Doi Not available
Year 2014
Literature 2
Pubmed ID 27129462
Title Cationic Antimicrobial Peptides Derived from Crocodylus siamensis Leukocyte Extract, Revealing Anticancer Activity and Apoptotic Induction on Human Cervical Cancer Cells
Doi Not available
Year 2016
Literature 3
Pubmed ID 23831136
Title Improving the antibacterial activity and selectivity of an ultra short peptide by hydrophobic and hydrophilic amino acid stretches
Doi Not available
Year 2013
Literature 4
Pubmed ID 21184776
Title Characterization of the novel antibacterial peptide Leucrocin from crocodile (Crocodylus siamensis) white blood cell extracts
Doi Not available
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 4726
This work is licensed under a Creative Commons Attribution 4.0 International License.