This work is licensed under a Creative Commons Attribution 4.0 International License.
Bactenecin-7 (1-35), Bac-7 (1-35)
General Information
DRACP ID DRACP03485
Peptide Name Bactenecin-7 (1-35), Bac-7 (1-35)
Sequence RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFP
Sequence Length 35
UniProt ID P19661
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C196H322N68O36
Absent amino acids ACDEHKMNQSTVWY
Common amino acids P
Mass 481369
Pl 13.5
Basic residues 11
Acidic residues 0
Hydrophobic residues 7
Net charge 11
Boman Index -13262
Hydrophobicity -141.43
Aliphatic Index 55.71
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33036159
Title Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens
Doi Not available
Year 2020
Literature 2
Pubmed ID 29526712
Title The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome
Doi Not available
Year 2018
Literature 3
Pubmed ID 28137800
Title The Mechanism of Killing by the Proline-Rich Peptide Bac7(1-35) against Clinical Strains of Pseudomonas aeruginosa Differs from That against Other Gram-Negative Bacteria
Doi Not available
Year 2017
Literature 4
Pubmed ID 15572192
Title Antimicrobial activity of Bac7 fragments against drug-resistant clinical isolates
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5243
This work is licensed under a Creative Commons Attribution 4.0 International License.