This work is licensed under a Creative Commons Attribution 4.0 International License.
Bactenecin-7 (1-16)
General Information
DRACP ID DRACP03487
Peptide Name Bactenecin-7 (1-16)
Sequence RRIRPRPPRLPRPRPR
Sequence Length 16
UniProt ID P19661
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C90H162N40O17
Absent amino acids ACDEFGHKMNQSTVWY
Common amino acids R
Mass 234422
Pl 13.35
Basic residues 8
Acidic residues 0
Hydrophobic residues 2
Net charge 8
Boman Index -10952
Hydrophobicity -233.13
Aliphatic Index 48.75
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34360723
Title Effects of Lipidation on a Proline-Rich Antibacterial Peptide
Doi Not available
Year 2021
Literature 2
Pubmed ID 32787108
Title Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens
Doi Not available
Year 2020
Literature 3
Pubmed ID 31209863
Title Identification and elucidation of proline-rich antimicrobial peptides with enhanced potency and delivery
Doi Not available
Year 2019
Literature 4
Pubmed ID 25525837
Title Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7
Doi Not available
Year 2015
Literature 5
Pubmed ID 15572192
Title Antimicrobial activity of Bac7 fragments against drug-resistant clinical isolates
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5248
This work is licensed under a Creative Commons Attribution 4.0 International License.