P18 N-3L
General Information
DRACP ID DRACP03488
Peptide Name P18 N-3L
Sequence KWFKKIPKFLHLLKKF
Sequence Length 16
UniProt ID P11006
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C109H169N25O17
Absent amino acids ACDEGMNQRSTVY
Common amino acids K
Mass 236943
Pl 11.5
Basic residues 7
Acidic residues 0
Hydrophobic residues 8
Net charge 7
Boman Index -701
Hydrophobicity -30
Aliphatic Index 97.5
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 366.67
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 12005420
Title Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs
Doi Not available
Year 2001
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5271