P18 N-3L

General Information


DRACP ID  DRACP03488

Peptide Name   P18 N-3L

Sequence  KWFKKIPKFLHLLKKF

Sequence Length  16

UniProt ID  P11006 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03488

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C109H169N25O17

Absent amino acids  ACDEGMNQRSTVY

Common amino acids  K

Mass  236943

Pl  11.5

Basic residues  7

Acidic residues  0

Hydrophobic residues  8

Net charge  7

Boman Index  -701

Hydrophobicity  -30

Aliphatic Index  97.5

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  366.67

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 12005420

Title  Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide, P18 and its analogs

Doi Not available

Year  2001

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  5271

DRACP is developed by Dr.Zheng's team.