This work is licensed under a Creative Commons Attribution 4.0 International License.
NA-Cathelicidin, NA-CATH
General Information
DRACP ID DRACP03492
Peptide Name NA-Cathelicidin, NA-CATH
Sequence KRFKKFFKKLKNSVKKRAKKFFKKPKVIGVTFPF
Sequence Length 34
UniProt ID B6S2X0
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C206H334N54O38
Absent amino acids CDEHMQWY
Common amino acids K
Mass 476401
Pl 12.66
Basic residues 15
Acidic residues 0
Hydrophobic residues 13
Net charge 15
Boman Index -6903
Hydrophobicity -76.47
Aliphatic Index 51.47
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27025629
Title Short, Synthetic peptide Cationic Peptides Have Antibacterial Activity against Mycobacterium smegmatis by Forming Pores in Membrane and Synergizing with Antibiotics
Doi Not available
Year 2015
Literature 2
Pubmed ID 28089718
Title Cathelicidin antimicrobial peptide from Alligator mississippiensis has antibacterial activity against multi-drug resistant Acinetobacter baumanii and Klebsiella pneumoniae
Doi Not available
Year 2017
Literature 3
Pubmed ID 25660753
Title Helical cationic antimicrobial peptide length and its impact on membrane disruption
Doi Not available
Year 2015
Literature 4
Pubmed ID 20399752
Title Antimicrobial and antibiofilm activity of cathelicidins and short, Synthetic peptide peptides against Francisella
Doi Not available
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 5396
This work is licensed under a Creative Commons Attribution 4.0 International License.