Chromogranin-A (344-358), bCGA(344-358), Catestatin, Cateslytin

General Information


DRACP ID  DRACP03504

Peptide Name   Chromogranin-A (344-358), bCGA(344-358), Catestatin, Cateslytin

Sequence  RSMRLSFRARGYGFR

Sequence Length  15

UniProt ID  L8HWJ5  P05059 

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03504

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C81H130N30O19S

Absent amino acids  CDEHIKNPQTVW

Common amino acids  R

Mass  211004

Pl  12.68

Basic residues  5

Acidic residues  0

Hydrophobic residues  4

Net charge  5

Boman Index  -6462

Hydrophobicity  -87.33

Aliphatic Index  32.67

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  1490

Absorbance 280nm  106.43

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 29915284

Title  D-Cateslytin: a new antifungal agent for the treatment of oral Candida albicans associated infections

Doi Not available

Year  2018

Literature 2

Pubmed ID 29123174

Title  D-Cateslytin, a new antimicrobial peptide with therapeutic potential

Doi Not available

Year  2017

Literature 3

Pubmed ID 15723172

Title  New antimicrobial activity for the catecholamine release-inhibitory peptide from chromogranin A

Doi Not available

Year  2005

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  5882

DRACP is developed by Dr.Zheng's team.