Pep27 [E4W][R19W][R22W][R26W]

General Information


DRACP ID  DRACP03505

Peptide Name   Pep27 [E4W][R19W][R22W][R26W]

Sequence  MRKWFHNVLSSGQLLADKWPAWDYNWK

Sequence Length  27

UniProt ID  Q9S4I9 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03505

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C160H226N42O38S

Absent amino acids  CEIT

Common amino acids  W

Mass  384182

Pl  10.12

Basic residues  5

Acidic residues  2

Hydrophobic residues  11

Net charge  3

Boman Index  -4142

Hydrophobicity  -79.63

Aliphatic Index  61.48

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  23490

Absorbance 280nm  903.46

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 16004618

Title  Functional and structural characteristics of anticancer peptide Pep27 analogues

Doi Not available

Year  2005

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  5911

DRACP is developed by Dr.Zheng's team.