This work is licensed under a Creative Commons Attribution 4.0 International License.
Tyrocidine A1
General Information
DRACP ID DRACP03513
Peptide Name Tyrocidine A1
Sequence fPFfNQYVKL
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Bacteria
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antiparasitic
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C49H69N11O10
Absent amino acids ACDEGHIMRSTW
Common amino acids FKLNPQVY
Mass 113286
Pl 9.3
Basic residues 1
Acidic residues 0
Hydrophobic residues 3
Net charge 1
Boman Index -593
Hydrophobicity -30
Aliphatic Index 68
Half Life
/
Extinction Coefficient cystines 1490
Absorbance 280nm 165.56
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 17462586
Title Inhibition of malaria parasite blood stages by tyrocidines, membrane-active cyclic peptide antibiotics from Bacillus brevis
Doi Not available
Year 2007
Literature 2
Pubmed ID 19586775
Title Anti-listerial activity and structure-activity relationships of the six major tyrocidines, cyclic decapeptides from Bacillus aneurinolyticus
Doi Not available
Year 2009
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 6090
This work is licensed under a Creative Commons Attribution 4.0 International License.