This work is licensed under a Creative Commons Attribution 4.0 International License.
Brevinin-1ZHb, Amurin-2b
General Information
DRACP ID DRACP03531
Peptide Name Brevinin-1ZHb, Amurin-2b
Sequence FLPLLLSALPSFLCLVFKKC
Sequence Length 20
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C111H178N22O23S2
Absent amino acids DEGHIMNQRTWY
Common amino acids L
Mass 259198
Pl 8.82
Basic residues 2
Acidic residues 0
Hydrophobic residues 12
Net charge 2
Boman Index 3389
Hydrophobicity 167
Aliphatic Index 156
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 125
Absorbance 280nm 6.58
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29366784
Title Identification of novel Amurin-2 variants from the skin secretion of Rana amurensis, and the design of cationicity-enhanced analogues
Doi Not available
Year 2018
Literature 2
Pubmed ID 22943778
Title Molecular cloning and functional characterization of novel antimicrobial peptides from the skin of brown frog, Rana zhenhaiensis
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 6703
This work is licensed under a Creative Commons Attribution 4.0 International License.