Cyclo(Leu-Val), Diketopiperazine (LV)

General Information


DRACP ID  DRACP03536

Peptide Name   Cyclo(Leu-Val), Diketopiperazine (LV)

Sequence  LV

Sequence Length  2

UniProt ID  Not available

PubChem CID  Not available

Origin  Bacteria

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03536

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C11H22N2O3

Absent amino acids  ACDEFGHIKMNPQRSTWY

Common amino acids  LV

Mass  24833

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  2

Net charge  0

Boman Index  896

Hydrophobicity  400

Aliphatic Index  340

Half Life 
  Mammalian: 100 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30270742

Title  Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXR伪 transcriptional regulation

Doi Not available

Year  2020

Literature 2

Pubmed ID 23979826

Title  Cyclic dipeptides from rhabditid entomopathogenic nematode-associated Bacillus cereus have antimicrobial activities

Doi Not available

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  6794

DRACP is developed by Dr.Zheng's team.