IDR-1002
General Information
DRACP ID DRACP03542
Peptide Name IDR-1002
Sequence VQRWLIVWRIRK
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C79H129N25O14
Absent amino acids ACDEFGHMNPSTY
Common amino acids R
Mass 184944
Pl 12.81
Basic residues 4
Acidic residues 0
Hydrophobic residues 7
Net charge 4
Boman Index -2835
Hydrophobicity -12.5
Aliphatic Index 145.83
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 11000
Absorbance 280nm 1000
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33242643
Title Host defense peptide IDR-1002 associated with ciprofloxacin as a new antimicrobial and immunomodulatory strategy for dental pulp revascularization therapy
Doi Not available
Year 2020
Literature 2
Pubmed ID 23555622
Title Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7110