IDR-1002

General Information


DRACP ID  DRACP03542

Peptide Name   IDR-1002

Sequence  VQRWLIVWRIRK

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03542

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C79H129N25O14

Absent amino acids  ACDEFGHMNPSTY

Common amino acids  R

Mass  184944

Pl  12.81

Basic residues  4

Acidic residues  0

Hydrophobic residues  7

Net charge  4

Boman Index  -2835

Hydrophobicity  -12.5

Aliphatic Index  145.83

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: >10 hour

Extinction Coefficient cystines  11000

Absorbance 280nm  1000

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33242643

Title  Host defense peptide IDR-1002 associated with ciprofloxacin as a new antimicrobial and immunomodulatory strategy for dental pulp revascularization therapy

Doi Not available

Year  2020

Literature 2

Pubmed ID 23555622

Title  Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  7110

DRACP is developed by Dr.Zheng's team.