This work is licensed under a Creative Commons Attribution 4.0 International License.
PMAP-36 (2-17) [K7,11W]
General Information
DRACP ID DRACP03550
Peptide Name PMAP-36 (2-17) [K7,11W]
Sequence RFRRLRWKTRWRLKKI
Sequence Length 16
UniProt ID P49931
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C107H179N39O18
Absent amino acids ACDEGHMNPQSVY
Common amino acids R
Mass 256756
Pl 13.21
Basic residues 9
Acidic residues 0
Hydrophobic residues 6
Net charge 9
Boman Index -8634
Hydrophobicity -164.38
Aliphatic Index 73.13
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 11000
Absorbance 280nm 733.33
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25818457
Title Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of ?-helix-based peptide amphiphiles
Doi Not available
Year 2015
Literature 2
Pubmed ID 25735802
Title Characterization of antimicrobial activity and mechanisms of low amphipathic peptides with different ?-helical propensity
Doi Not available
Year 2015
Literature 3
Pubmed ID 24021230
Title Design of imperfectly amphipathic ?-helical antimicrobial peptides with enhanced cell selectivity
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7145
This work is licensed under a Creative Commons Attribution 4.0 International License.