This work is licensed under a Creative Commons Attribution 4.0 International License.
Buforin-2 (5-21), sh-Buforin
General Information
DRACP ID DRACP03567
Peptide Name Buforin-2 (5-21), sh-Buforin
Sequence RAGLQFPVGRVHRLLRK
Sequence Length 17
UniProt ID P55897
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C90H155N33O19
Absent amino acids CDEIMNSTWY
Common amino acids R
Mass 228900
Pl 12.98
Basic residues 6
Acidic residues 0
Hydrophobic residues 7
Net charge 6
Boman Index -4592
Hydrophobicity -38.82
Aliphatic Index 108.82
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25891844
Title Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity
Doi Not available
Year 2015
Literature 2
Pubmed ID 28314993
Title Comparative analysis of internalisation, haemolytic, cytotoxic and antibacterial effect of membrane-active cationic peptides: aspects of experimental setup
Doi Not available
Year 2017
Literature 3
Pubmed ID 24803240
Title Improved bioactivity of antimicrobial peptides by addition of amino-terminal copper and nickel (ATCUN) binding motifs
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7651
This work is licensed under a Creative Commons Attribution 4.0 International License.