This work is licensed under a Creative Commons Attribution 4.0 International License.
Act Beta-defensin 2 (18-40)[C12I,G14p,P15G,C-del]
General Information
DRACP ID DRACP03570
Peptide Name Act Beta-defensin 2 (18-40)[C12I,G14p,P15G,C-del]
Sequence RCpGRTRQIGTIFpGRIKCRSW
Sequence Length 22
UniProt ID P46160
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C102H168N38O23S2
Absent amino acids ADEHLMNPVY
Common amino acids R
Mass 273356
Pl 12.33
Basic residues 6
Acidic residues 0
Hydrophobic residues 5
Net charge 6
Boman Index -6878
Hydrophobicity -58.64
Aliphatic Index 53.18
Half Life
/
Extinction Coefficient cystines 5625
Absorbance 280nm 267.86
Polar residues 8
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25791057
Title N-terminal fatty acylation of peptides spanning the cationic C-terminal segment of bovine ?-defensin-2 results in salt-resistant antibacterial activity
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7713
This work is licensed under a Creative Commons Attribution 4.0 International License.