PMAP-36 (2-17) [T9W]
General Information
DRACP ID DRACP03579
Peptide Name PMAP-36 (2-17) [T9W]
Sequence RFRRLRKKWRKRLKKI
Sequence Length 16
UniProt ID P49931
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C104H186N40O17
Absent amino acids ACDEGHMNPQSTVY
Common amino acids R
Mass 253659
Pl 13.21
Basic residues 11
Acidic residues 0
Hydrophobic residues 5
Net charge 11
Boman Index -9720
Hydrophobicity -203.13
Aliphatic Index 73.13
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 366.67
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25753629
Title Bactericidal efficiency and modes of action of the novel antimicrobial peptide T9W against Pseudomonas aeruginosa
Doi Not available
Year 2015
Literature 2
Pubmed ID 25494332
Title Importance of Tryptophan in Transforming an Amphipathic Peptide into a Pseudomonas aeruginosa-Targeted Antimicrobial Peptide
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 7768