Neocryptolepine 9(GG)

General Information


DRACP ID  DRACP03581

Peptide Name   Neocryptolepine 9(GG)

Sequence  GG

Sequence Length  2

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP03581

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  DiMIQ

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C4H8N2O3

Absent amino acids  ACDEFHIKLMNPQRSTVWY

Common amino acids  G

Mass  15014

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  0

Net charge  0

Boman Index  188

Hydrophobicity  -40

Aliphatic Index  0

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22574992

Title  Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents

Doi Not available

Year  2012

Literature 2

Pubmed ID 24686017

Title  Searching for new derivatives of neocryptolepine: synthesis, antiproliferative, antimicrobial and antifungal activities

Doi Not available

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  7790

DRACP is developed by Dr.Zheng's team.