This work is licensed under a Creative Commons Attribution 4.0 International License.
Brevinin-2CE
General Information
DRACP ID DRACP03592
Peptide Name Brevinin-2CE
Sequence GLLSVFKGVLKTAGKNVAKNVAGSLLDQLKCKISGGC
Sequence Length 37
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C164H286N46O47S2
Absent amino acids EHMPRWY
Common amino acids GKL
Mass 436082
Pl 10.51
Basic residues 6
Acidic residues 1
Hydrophobic residues 15
Net charge 5
Boman Index -640
Hydrophobicity 38.92
Aliphatic Index 113.24
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 125
Absorbance 280nm 3.47
Polar residues 14
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24474334
Title In vitro synergistic activities of antimicrobial peptide brevinin-2CE with five kinds of antibiotics against multidrug-resistant clinical isolates
Doi Not available
Year 2014
Literature 2
Pubmed ID 21303203
Title Molecular cloning of novel antimicrobial peptide genes from the skin of the Chinese brown frog, Rana chensinensis
Doi Not available
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8065
This work is licensed under a Creative Commons Attribution 4.0 International License.