This work is licensed under a Creative Commons Attribution 4.0 International License.
Coprisin (22-30)[H23L]
General Information
DRACP ID DRACP03594
Peptide Name Coprisin (22-30)[H23L]
Sequence LLCIALRKK
Sequence Length 9
UniProt ID A9XFZ7
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C48H92N14O10S
Absent amino acids DEFGHMNPQSTVWY
Common amino acids L
Mass 120030
Pl 10.79
Basic residues 3
Acidic residues 0
Hydrophobic residues 5
Net charge 3
Boman Index -325
Hydrophobicity 87.78
Aliphatic Index 184.44
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22297233
Title Effects of the Synthetic peptide coprisin analog peptide, CopA3 in pathogenic microorganisms and mammalian cancer cells
Doi Not available
Year 2012
Literature 2
Pubmed ID 24321546
Title Synthesis and antimicrobial activity of cysteine-free coprisin nonapeptides
Doi Not available
Year 2014
Literature 3
Pubmed ID 24393527
Title Structure-activity relationships of the intramolecular disulfide bonds in coprisin, a defensin from the dung beetle
Doi Not available
Year 2014
Literature 4
Pubmed ID 20721297
Title Isolation and Characterization of a Defensin-Like Peptide (Coprisin) from the Dung Beetle, Copris tripartitus
Doi Not available
Year 2009
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8070
This work is licensed under a Creative Commons Attribution 4.0 International License.