This work is licensed under a Creative Commons Attribution 4.0 International License.
AaeAP1 [S4,8,15K; A11K, N19K]
General Information
DRACP ID DRACP03601
Peptide Name AaeAP1 [S4,8,15K; A11K, N19K]
Sequence FLFKLIPKVIKGLVKAIRK
Sequence Length 19
UniProt ID A0A060QQ43
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C110H191N27O20
Absent amino acids CDEHMNQSTWY
Common amino acids K
Mass 253315
Pl 12.05
Basic residues 6
Acidic residues 0
Hydrophobic residues 11
Net charge 6
Boman Index 364
Hydrophobicity 77.37
Aliphatic Index 158.95
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25626077
Title AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of bioSynthetic peptide precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8153
This work is licensed under a Creative Commons Attribution 4.0 International License.