AaeAP1 [S4,8,15K; A11K, N19K]

General Information


DRACP ID  DRACP03601

Peptide Name   AaeAP1 [S4,8,15K; A11K, N19K]

Sequence  FLFKLIPKVIKGLVKAIRK

Sequence Length  19

UniProt ID  A0A060QQ43 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C110H191N27O20

Absent amino acids  CDEHMNQSTWY

Common amino acids  K

Mass  253315

Pl  12.05

Basic residues  6

Acidic residues  0

Hydrophobic residues  11

Net charge  6

Boman Index  364

Hydrophobicity  77.37

Aliphatic Index  158.95

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25626077

Title  AaeAP1 and AaeAP2: novel antimicrobial peptides from the venom of the scorpion, Androctonus aeneas: structural characterisation, molecular cloning of bioSynthetic peptide precursor-encoding cDNAs and engineering of analogues with enhanced antimicrobial and anticancer activities

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8153

DRACP is developed by Dr.Zheng's team.