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Papiliocin (1-8) - P - Magainin 2 (4-12)
General Information
DRACP ID DRACP03607
Peptide Name Papiliocin (1-8) - P - Magainin 2 (4-12)
Sequence RWKIFKKIPKFLHSAKKF
Sequence Length 18
UniProt ID P11006
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C115H180N30O20
Absent amino acids CDEGMNQTVY
Common amino acids K
Mass 260628
Pl 12.1
Basic residues 8
Acidic residues 0
Hydrophobic residues 8
Net charge 8
Boman Index -2844
Hydrophobicity -63.33
Aliphatic Index 70.56
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 323.53
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26053120
Title Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8212
This work is licensed under a Creative Commons Attribution 4.0 International License.