Papiliocin (1-8) - P - Magainin 2 (4-12)

General Information


DRACP ID  DRACP03607

Peptide Name   Papiliocin (1-8) - P - Magainin 2 (4-12)

Sequence  RWKIFKKIPKFLHSAKKF

Sequence Length  18

UniProt ID  P11006 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C115H180N30O20

Absent amino acids  CDEGMNQTVY

Common amino acids  K

Mass  260628

Pl  12.1

Basic residues  8

Acidic residues  0

Hydrophobic residues  8

Net charge  8

Boman Index  -2844

Hydrophobicity  -63.33

Aliphatic Index  70.56

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  323.53

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 26053120

Title  Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8212

DRACP is developed by Dr.Zheng's team.