This work is licensed under a Creative Commons Attribution 4.0 International License.
OsDef2 (16-37)
General Information
DRACP ID DRACP03610
Peptide Name OsDef2 (16-37)
Sequence KGIRGYKGGYCKGAFKQTCKCY
Sequence Length 22
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C109H171N31O28S3
Absent amino acids DEHLMNPSVW
Common amino acids GK
Mass 283469
Pl 10.03
Basic residues 6
Acidic residues 0
Hydrophobic residues 3
Net charge 6
Boman Index -3295
Hydrophobicity -79.55
Aliphatic Index 22.27
Half Life
Mammalian: 3.5 hour
Yeast: 10 min
E.coli: >10 hour
Extinction Coefficient cystines 4595
Absorbance 280nm 218.81
Polar residues 12
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34866278
Title Antifungal activity and mode of action of Synthetic peptide peptides derived from the tick OsDef2 defensin
Doi Not available
Year 2022
Literature 2
Pubmed ID 31713951
Title Antimicrobial Function of Short Amidated Peptide Fragments From the Tick-Derived OsDef2 Defensin
Doi Not available
Year 2019
Literature 3
Pubmed ID 26215047
Title Investigation into the mechanism of action of the antimicrobial peptides Os and Os-C derived from a tick defensin
Doi Not available
Year 2015
Literature 4
Pubmed ID 23553969
Title Structural and functional characterization of peptides derived from the carboxy-terminal region of a defensin from the tick Ornithodoros savignyi
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8286
This work is licensed under a Creative Commons Attribution 4.0 International License.