Peptide P [L21A]

General Information


DRACP ID  DRACP03614

Peptide Name   Peptide P [L21A]

Sequence  KWKSFLKTFKSAKKTVLHTAAKAISS

Sequence Length  26

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C136H224N36O34

Absent amino acids  CDEGMNPQRY

Common amino acids  K

Mass  335359

Pl  11.58

Basic residues  8

Acidic residues  0

Hydrophobic residues  11

Net charge  8

Boman Index  -3049

Hydrophobicity  -29.23

Aliphatic Index  71.54

Half Life 
  Mammalian: 1 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  220

Polar residues  7

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 21252288

Title  Studies on mechanism of action of anticancer peptides by modulation of hydrophobicity within a defined structural framework

Doi Not available

Year  2011

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8383

DRACP is developed by Dr.Zheng's team.