This work is licensed under a Creative Commons Attribution 4.0 International License.
A3-APO
General Information
DRACP ID DRACP03617
Peptide Name A3-APO
Sequence XRPDKPRPYLPRPRPPRPVRX,XRPDKPRPYLPRPRPPRPVR
Sequence Length 42
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral Mix
Physicochemical Information
Formula C212H342N76O41
Absent amino acids ACEFGHIMNQSTW
Common amino acids P
Mass 567292
Pl 12.65
Basic residues 14
Acidic residues 2
Hydrophobic residues 4
Net charge 12
Boman Index -18994
Hydrophobicity -192.86
Aliphatic Index 32.38
Half Life
/
Extinction Coefficient cystines 2980
Absorbance 280nm 72.68
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26384569
Title Multimerization of a Proline-Rich Antimicrobial Peptide, Chex-Arg20, Alters Its Mechanism of Interaction with the Escherichia coli Membrane
Doi Not available
Year 2015
Literature 2
Pubmed ID 30155456
Title Synergy Between Proline-Rich Antimicrobial Peptides and Small Molecule Antibiotics Against Selected Gram-Negative Pathogens in vitro and in vivo
Doi Not available
Year 2018
Literature 3
Pubmed ID 18721837
Title Scope and limitations of the designer proline-rich antibacterial peptide dimer, A3-APO, alone or in synergy with conventional antibiotics
Doi Not available
Year 2008
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8554
This work is licensed under a Creative Commons Attribution 4.0 International License.