This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclotide Vigno 5
General Information
DRACP ID DRACP03618
Peptide Name Cyclotide Vigno 5
Sequence GLPLCGETCVGGTCNTPGCSCGWPVCVRN
Sequence Length 29
UniProt ID Not available
PubChem CID Not available
Origin Plantae
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C117H187N35O38S6
Absent amino acids ADFHIKMQY
Common amino acids CG
Mass 338397
Pl 5.94
Basic residues 1
Acidic residues 1
Hydrophobic residues 6
Net charge 0
Boman Index -851
Hydrophobicity 31.72
Aliphatic Index 56.9
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 5875
Absorbance 280nm 209.82
Polar residues 18
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26751970
Title Viola plant cyclotide vigno 5 induces mitochondria-mediated apoptosis via cytochrome C release and caspases activation in cervical cancer cells
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8715
This work is licensed under a Creative Commons Attribution 4.0 International License.