This work is licensed under a Creative Commons Attribution 4.0 International License.
Dengue virus peptide fragment VG16 [D2A;G6,8K;N7R;G10P], VG16KRKP
General Information
DRACP ID DRACP03621
Peptide Name Dengue virus peptide fragment VG16 [D2A;G6,8K;N7R;G10P], VG16KRKP
Sequence VARGWKRKCPLFGKGG
Sequence Length 16
UniProt ID O39650
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C80H130N26O17S
Absent amino acids DEHIMNQSTY
Common amino acids G
Mass 202787
Pl 11.75
Basic residues 5
Acidic residues 0
Hydrophobic residues 5
Net charge 5
Boman Index -2537
Hydrophobicity -60.63
Aliphatic Index 48.75
Half Life
Mammalian: 3.5 hour
Yeast: 10 min
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 366.67
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31383740
Title Structural insights into the combinatorial effects of antimicrobial peptides reveal a role of aromatic-aromatic interactions in antibacterial synergism
Doi Not available
Year 2019
Literature 2
Pubmed ID 35753394
Title Structural insights into the interaction of antifungal peptides and ergosterol containing fungal membrane
Doi Not available
Year 2022
Literature 3
Pubmed ID 26407061
Title Designing potent antimicrobial peptides by disulphide linked dimerization and N-terminal lipidation to increase antimicrobial activity and membrane perturbation: Structural insights into lipopolysaccharide binding
Doi Not available
Year 2016
Literature 4
Pubmed ID 26144972
Title Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8811
This work is licensed under a Creative Commons Attribution 4.0 International License.