This work is licensed under a Creative Commons Attribution 4.0 International License.
Hp1404
General Information
DRACP ID DRACP03623
Peptide Name Hp1404
Sequence GILGKLWEGVKSIF
Sequence Length 14
UniProt ID P0DME6
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C75H119N17O18
Absent amino acids ACDHMNPQRTY
Common amino acids G
Mass 177894
Pl 9.54
Basic residues 2
Acidic residues 1
Hydrophobic residues 7
Net charge 1
Boman Index 1054
Hydrophobicity 67.14
Aliphatic Index 132.14
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34073939
Title Comparative Antimicrobial Activity of Hp404 Peptide and Its Analogs against Acinetobacter baumannii
Doi Not available
Year 2021
Literature 2
Pubmed ID 34022355
Title Identification of the scorpion venom-derived antimicrobial peptide Hp1404 as a new antimicrobial agent against carbapenem-resistant Acinetobacter baumannii
Doi Not available
Year 2021
Literature 3
Pubmed ID 29379033
Title Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa
Doi Not available
Year 2018
Literature 4
Pubmed ID 24826994
Title Hp1404, a new antimicrobial peptide from the scorpion Heterometrus petersii
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8864
This work is licensed under a Creative Commons Attribution 4.0 International License.