This work is licensed under a Creative Commons Attribution 4.0 International License.
Melittin [I17K]
General Information
DRACP ID DRACP03624
Peptide Name Melittin [I17K]
Sequence GIGAVLKVLTTGLPALKSWIKRKRQQ
Sequence Length 26
UniProt ID P01501
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C131H229N39O32
Absent amino acids CDEFHMNY
Common amino acids KL
Mass 330862
Pl 12.56
Basic residues 6
Acidic residues 0
Hydrophobic residues 11
Net charge 6
Boman Index -2529
Hydrophobicity -5
Aliphatic Index 120
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 220
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27011349
Title Characterization of antimicrobial activity against Listeria and cytotoxicity of native melittin and its mutant variants
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8871
This work is licensed under a Creative Commons Attribution 4.0 International License.