This work is licensed under a Creative Commons Attribution 4.0 International License.
EeCentrocin 1 Chain A
General Information
DRACP ID DRACP03626
Peptide Name EeCentrocin 1 Chain A
Sequence GWWRRTVDKVRNAGRKVAGFASKACGALGH
Sequence Length 30
UniProt ID A0A144LUY5
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C143H228N50O36S
Absent amino acids EIMPQY
Common amino acids AG
Mass 377322
Pl 12.1
Basic residues 8
Acidic residues 1
Hydrophobic residues 12
Net charge 7
Boman Index -6261
Hydrophobicity -48.33
Aliphatic Index 58.67
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 11000
Absorbance 280nm 379.31
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32403086
Title Antimicrobial and antibiofilm activity of the EeCentrocin 1 derived peptide EC1-17KV via membrane disruption
Doi Not available
Year 2020
Literature 2
Pubmed ID 31802582
Title Structure-activity Relationship Studies of Shortened Analogues of the Antimicrobial Peptide EeCentrocin 1 From the Sea Urchin Echinus Esculentus
Doi Not available
Year 2019
Literature 3
Pubmed ID 27007817
Title Novel Antimicrobial Peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible Sea Urchin Echinus esculentus Have 6-Br-Trp Post-Translational Modifications
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8873
This work is licensed under a Creative Commons Attribution 4.0 International License.