rApoE (133-150)

General Information


DRACP ID  DRACP03627

Peptide Name   rApoE (133-150)

Sequence  PMLRVRLASHLRKLRKRLLR

Sequence Length  20

UniProt ID  P02649 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C111H206N42O22S

Absent amino acids  CDEFGINQTWY

Common amino acids  LR

Mass  285226

Pl  13.2

Basic residues  9

Acidic residues  0

Hydrophobic residues  8

Net charge  9

Boman Index  -7096

Hydrophobicity  -48.5

Aliphatic Index  136.5

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 27028511

Title  A new cryptic cationic antimicrobial peptide (AMP) from human apolipoprotein E with anti-bacterial activity and immunomodulatory effects on human cells

Doi Not available

Year  2016

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  8920

DRACP is developed by Dr.Zheng's team.