This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin PD-1
General Information
DRACP ID DRACP03631
Peptide Name Dermaseptin PD-1
Sequence GMWSKIKETAMAAAKEAAKAAGKTISDMIKQ
Sequence Length 31
UniProt ID A0A0X8XRJ2
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C141H241N39O43S3
Absent amino acids CFHLNPRVY
Common amino acids A
Mass 380220
Pl 10.5
Basic residues 6
Acidic residues 3
Hydrophobic residues 12
Net charge 3
Boman Index -3262
Hydrophobicity -27.42
Aliphatic Index 63.55
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 183.33
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27187467
Title Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 9179
This work is licensed under a Creative Commons Attribution 4.0 International License.