Temporin-SHf [S5R]

General Information


DRACP ID  DRACP03643

Peptide Name   Temporin-SHf [S5R]

Sequence  FFFLRRIF

Sequence Length  8

UniProt ID  D4YWD1 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C60H84N14O9

Absent amino acids  ACDEGHKMNPQSTVWY

Common amino acids  F

Mass  127044

Pl  12.5

Basic residues  2

Acidic residues  0

Hydrophobic residues  6

Net charge  2

Boman Index  -808

Hydrophobicity  131.25

Aliphatic Index  97.5

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 26181487

Title  Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  9488

DRACP is developed by Dr.Zheng's team.