Laterosporulin 10

General Information


DRACP ID  DRACP03647

Peptide Name   Laterosporulin 10

Sequence  ACVNQCPDAIDRFIVKDKGCHGVEKKYYKQVYVACMNGQHLYCRTEWGGPCQL

Sequence Length  53

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  6LWZ 

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C265H407N75O75S7

Absent amino acids  S

Common amino acids  CGKV

Mass  699577

Pl  8.11

Basic residues  9

Acidic residues  5

Hydrophobic residues  14

Net charge  4

Boman Index  -7991

Hydrophobicity  -42.83

Aliphatic Index  62.45

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  11835

Absorbance 280nm  227.6

Polar residues  18

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28422156

Title  Anticancer properties of a defensin like class IId bacteriocin Laterosporulin10

Doi Not available

Year  2017

Literature 2

Pubmed ID 27267959

Title  Laterosporulin10: a novel defensin like Class IId bacteriocin from Brevibacillus sp strain SKDU10 with inhibitory activity against microbial pathogens

Doi Not available

Year  2016

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  9529

DRACP is developed by Dr.Zheng's team.