Cecropin A (1鈥?)

General Information


DRACP ID  DRACP03654

Peptide Name   Cecropin A (1鈥?)

Sequence  KWKLFKKI

Sequence Length  8

UniProt ID  P01507 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C56H91N13O9

Absent amino acids  ACDEGHMNPQRSTVY

Common amino acids  K

Mass  121546

Pl  11.28

Basic residues  4

Acidic residues  0

Hydrophobic residues  4

Net charge  4

Boman Index  -705

Hydrophobicity  -67.5

Aliphatic Index  97.5

Half Life 
  Mammalian: 20 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  785.71

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32098142

Title  Hybridization With Insect Cecropin A (1-8) Improve the Stability and Selectivity of Naturally Occurring Peptides

Doi Not available

Year  2020

Literature 2

Pubmed ID 28178190

Title  High Specific Selectivity and Membrane-Active Mechanism of Synthetic peptide Cationic Hybrid Antimicrobial Peptides Based on the Peptide FV7

Doi Not available

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  9963

DRACP is developed by Dr.Zheng's team.