Modified Clavanin A

General Information


DRACP ID  DRACP03661

Peptide Name   Modified Clavanin A

Sequence  FLPIIVFQFLGKIIHHVGNFVHGFSHVF

Sequence Length  28

UniProt ID  P80710 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antiviral; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C163H233N39O32

Absent amino acids  ACDEMRTWY

Common amino acids  F

Mass  373267

Pl  9.71

Basic residues  5

Acidic residues  0

Hydrophobic residues  16

Net charge  5

Boman Index  2661

Hydrophobicity  113.93

Aliphatic Index  125

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 27804992

Title  An anti-infective Synthetic peptide peptide with dual antimicrobial and immunomodulatory activities

Doi Not available

Year  2016

Literature 2

Pubmed ID 27161201

Title  Linear Antimicrobial Peptides With Activity Against Herpes Simplex Virus 1 and Aichi Virus

Doi Not available

Year  2017

Literature 3

Pubmed ID 28712894

Title  Antimicrobial and immunomodulatory activity of host defense peptides, clavanins and LL-37, in vitro: An endodontic perspective

Doi Not available

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  10589

DRACP is developed by Dr.Zheng's team.