This work is licensed under a Creative Commons Attribution 4.0 International License.
As Cathelicidin 5, As-CATH5
General Information
DRACP ID DRACP03662
Peptide Name As Cathelicidin 5, As-CATH5
Sequence TRRKFWKKVLNGALKIAPFLLG
Sequence Length 22
UniProt ID A0A1U7RV49
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C123H202N34O25
Absent amino acids CDEHMQSY
Common amino acids KL
Mass 293193
Pl 12.56
Basic residues 6
Acidic residues 0
Hydrophobic residues 11
Net charge 6
Boman Index -1882
Hydrophobicity 4.55
Aliphatic Index 110.91
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 261.9
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36283984
Title Hydrophobicity Determines the Bacterial Killing Rate of δΌͺ-Helical Antimicrobial Peptides and Influences the Bacterial Resistance Development
Doi Not available
Year 2022
Literature 2
Pubmed ID 29017942
Title As-CATH4 and 5, two vertebrate-derived natural host defense peptides, enhance the immuno-resistance efficiency against bacterial infections in Chinese mitten crab, Eriocheir sinensis
Doi Not available
Year 2017
Literature 3
Pubmed ID 28798159
Title As-CATH1-6, novel cathelicidins with potent antimicrobial and immunomodulatory properties from Alligator sinensis, play pivotal roles in host antimicrobial immune responses
Doi Not available
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 10591
This work is licensed under a Creative Commons Attribution 4.0 International License.