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As Cathelicidin 6, As-CATH6
General Information
DRACP ID DRACP03663
Peptide Name As Cathelicidin 6, As-CATH6
Sequence TRWLWLLRGGLKAAGWGIRAHLNRNQ
Sequence Length 26
UniProt ID A0A1U7S6I2
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C139H219N47O31
Absent amino acids CDEFMPSVY
Common amino acids L
Mass 349069
Pl 12.98
Basic residues 6
Acidic residues 0
Hydrophobic residues 12
Net charge 6
Boman Index -4558
Hydrophobicity -45
Aliphatic Index 101.54
Half Life
Mammalian: 7.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 16500
Absorbance 280nm 660
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28798159
Title As-CATH1-6, novel cathelicidins with potent antimicrobial and immunomodulatory properties from Alligator sinensis, play pivotal roles in host antimicrobial immune responses
Doi Not available
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 10592
This work is licensed under a Creative Commons Attribution 4.0 International License.