LL-37 KR-12-a5 [L6l]

General Information


DRACP ID  DRACP03665

Peptide Name   LL-37 KR-12-a5 [L6l]

Sequence  KRIVKlILKWLR

Sequence Length  12

UniProt ID  P49913 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C70H123N21O11

Absent amino acids  ACDEFGHMNPQSTY

Common amino acids  K

Mass  163127

Pl  12.55

Basic residues  5

Acidic residues  0

Hydrophobic residues  6

Net charge  5

Boman Index  -2044

Hydrophobicity  -6.67

Aliphatic Index  154.17

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  500

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28525841

Title  LL-37-derived short antimicrobial peptide KR-12-a5 and its d-amino acid substituted analogs with cell selectivity, anti-biofilm activity, synergistic effect with conventional antibiotics, and anti-inflammatory activity

Doi Not available

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  10786

DRACP is developed by Dr.Zheng's team.