This work is licensed under a Creative Commons Attribution 4.0 International License.
LL-37 (15-32)[Q8K,D12K,N16K]
General Information
DRACP ID DRACP03679
Peptide Name LL-37 (15-32)[Q8K,D12K,N16K]
Sequence KEFKRIVKRIKKFLRKLV
Sequence Length 18
UniProt ID P49913
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C111H197N33O21
Absent amino acids ACDGHMNPQSTWY
Common amino acids K
Mass 263339
Pl 12.31
Basic residues 9
Acidic residues 1
Hydrophobic residues 8
Net charge 8
Boman Index -5115
Hydrophobicity -54.44
Aliphatic Index 118.89
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23689720
Title Cationic antimicrobial peptides and biogenic silver nanoparticles kill mycobacteria without eliciting DNA damage and cytotoxicity in mouse macrophages
Doi Not available
Year 2013
Literature 2
Pubmed ID 21790937
Title Cathelicidin is involved in the intracellular killing of mycobacteria in macrophages
Doi Not available
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11036
This work is licensed under a Creative Commons Attribution 4.0 International License.