Sublancin 168

General Information


DRACP ID  DRACP03702

Peptide Name   Sublancin 168

Sequence  GLGKAQCAALWLQCASGGTIGXGGGAVACQNYRQFCR

Sequence Length  37

UniProt ID  A0A1J5X031  P68578  P68577 

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  2MIJ 

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C153H241N49O44S4

Absent amino acids  DEHMP

Common amino acids  G

Mass  435150

Pl  8.68

Basic residues  3

Acidic residues  0

Hydrophobic residues  13

Net charge  3

Boman Index  -1777

Hydrophobicity  17.3

Aliphatic Index  66.22

Half Life 
  /

Extinction Coefficient cystines  7240

Absorbance 280nm  201.11

Polar residues  16

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 29854837

Title  Prevention of Cyclophosphamide-Induced Immunosuppression in Mice with the Antimicrobial Peptide Sublancin

Doi Not available

Year  2018

Literature 2

Pubmed ID 9722542

Title  the chemical and biological properties of, sublancin 168, a novel lantibiotic produced by Bacillus subtilis 168

Doi Not available

Year  1998

Literature 3

Pubmed ID 28906115

Title  Use of the Antimicrobial Peptide Sublancin with Combined Antibacterial and Immunomodulatory Activities To Protect against Methicillin-Resistant Staphylococcus aureus Infection in Mice

Doi Not available

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  11467

DRACP is developed by Dr.Zheng's team.