Sublancin 168
General Information
DRACP ID DRACP03702
Peptide Name Sublancin 168
Sequence GLGKAQCAALWLQCASGGTIGXGGGAVACQNYRQFCR
Sequence Length 37
UniProt ID A0A1J5X031 P68578 P68577
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C153H241N49O44S4
Absent amino acids DEHMP
Common amino acids G
Mass 435150
Pl 8.68
Basic residues 3
Acidic residues 0
Hydrophobic residues 13
Net charge 3
Boman Index -1777
Hydrophobicity 17.3
Aliphatic Index 66.22
Half Life
/
Extinction Coefficient cystines 7240
Absorbance 280nm 201.11
Polar residues 16
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29854837
Title Prevention of Cyclophosphamide-Induced Immunosuppression in Mice with the Antimicrobial Peptide Sublancin
Doi Not available
Year 2018
Literature 2
Pubmed ID 9722542
Title the chemical and biological properties of, sublancin 168, a novel lantibiotic produced by Bacillus subtilis 168
Doi Not available
Year 1998
Literature 3
Pubmed ID 28906115
Title Use of the Antimicrobial Peptide Sublancin with Combined Antibacterial and Immunomodulatory Activities To Protect against Methicillin-Resistant Staphylococcus aureus Infection in Mice
Doi Not available
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11467