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Dermaseptin DRS-DU-1 (1-13), DP-1
General Information
DRACP ID DRACP03711
Peptide Name Dermaseptin DRS-DU-1 (1-13), DP-1
Sequence ALWKSLLKNVGKA
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C67H114N18O16
Absent amino acids CDEFHIMPQRTY
Common amino acids KL
Mass 164199
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 7
Net charge 3
Boman Index -100
Hydrophobicity 14.62
Aliphatic Index 127.69
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 458.33
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30258724
Title Discovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11806
This work is licensed under a Creative Commons Attribution 4.0 International License.