This work is licensed under a Creative Commons Attribution 4.0 International License.
TAT(48-57)-G-Dermaseptin DRS-DU-1 (1-13), DP-2
General Information
DRACP ID DRACP03712
Peptide Name TAT(48-57)-G-Dermaseptin DRS-DU-1 (1-13), DP-2
Sequence GRKKRRQRRRGALWKSLLKNVGKA
Sequence Length 24
UniProt ID P04610
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C124H224N50O28
Absent amino acids CDEFHIMPTY
Common amino acids R
Mass 327388
Pl 13.21
Basic residues 11
Acidic residues 0
Hydrophobic residues 7
Net charge 11
Boman Index -10528
Hydrophobicity -155
Aliphatic Index 69.17
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 239.13
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30258724
Title Discovery of two skin-derived dermaseptins and design of a TAT-fusion analogue with broad-spectrum antimicrobial activity and low cytotoxicity on healthy cells
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11807
This work is licensed under a Creative Commons Attribution 4.0 International License.