This work is licensed under a Creative Commons Attribution 4.0 International License.
SRP-2
General Information
DRACP ID DRACP03718
Peptide Name SRP-2
Sequence GFALAGLARILCLWFREFSGFFRRLNRRFAMRRR
Sequence Length 34
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C193H301N63O39S2
Absent amino acids DHKPQTVY
Common amino acids R
Mass 478081
Pl 12.8
Basic residues 9
Acidic residues 1
Hydrophobic residues 17
Net charge 8
Boman Index -8771
Hydrophobicity 4.41
Aliphatic Index 80.59
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 166.67
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30279591
Title An engineered arginine-rich ?-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11819
This work is licensed under a Creative Commons Attribution 4.0 International License.