This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin DMS-DA6
General Information
DRACP ID DRACP03730
Peptide Name Dermaseptin DMS-DA6
Sequence GVWGIAKIAGKVLGNILPHVFSSNQS
Sequence Length 26
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C124H198N34O33
Absent amino acids CDEMRTY
Common amino acids G
Mass 313926
Pl 10.81
Basic residues 3
Acidic residues 0
Hydrophobic residues 12
Net charge 3
Boman Index 463
Hydrophobicity 46.54
Aliphatic Index 116.15
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 220
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30325956
Title Peptidoglycan potentiates the membrane disrupting effect of the carboxyamidated form of DMS-DA6, a Gram-positive selective antimicrobial peptide isolated from Pachymedusa dacnicolor skin
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 11989
This work is licensed under a Creative Commons Attribution 4.0 International License.