Cathelicidin (135-146), Tylotoin

General Information


DRACP ID  DRACP03732

Peptide Name   Cathelicidin (135-146), Tylotoin

Sequence  KCVRQNNKRVCK

Sequence Length  12

UniProt ID  W0FJD1 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C59H110N24O16S2

Absent amino acids  ADEFGHILMPSTWY

Common amino acids  K

Mass  167218

Pl  11.06

Basic residues  5

Acidic residues  0

Hydrophobic residues  2

Net charge  5

Boman Index  -5467

Hydrophobicity  -148.33

Aliphatic Index  48.33

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  125

Absorbance 280nm  11.36

Polar residues  4

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30389988

Title  Design of a novel cell-permeable chimeric peptide to promote wound healing

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12017

DRACP is developed by Dr.Zheng's team.