Hemagglutinin (347-367)[E4G,E7A]-Tat (48鈥?0); N-E5L-Tat (48鈥?0)

General Information


DRACP ID  DRACP03736

Peptide Name   Hemagglutinin (347-367)[E4G,E7A]-Tat (48鈥?0); N-E5L-Tat (48鈥?0)

Sequence  GLLEALAELLEGRKKRRQRRRPPQ

Sequence Length  24

UniProt ID  D2DUQ8 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C123H220N46O33

Absent amino acids  CDFHIMNSTVWY

Common amino acids  R

Mass  328181

Pl  12.22

Basic residues  8

Acidic residues  3

Hydrophobic residues  7

Net charge  5

Boman Index  -10203

Hydrophobicity  -140.42

Aliphatic Index  89.58

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 27713223

Title  Fusion of a Short HA2-Derived Peptide Sequence to Cell-Penetrating Peptides Improves Cytosolic Uptake, but Enhances Cytotoxic Activity

Doi Not available

Year  2009

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12032

DRACP is developed by Dr.Zheng's team.