Hemagglutinin (347-367)[E4G,E7A]-Tat (48鈥?0); N-E5L-Tat (48鈥?0)
General Information
DRACP ID DRACP03736
Peptide Name Hemagglutinin (347-367)[E4G,E7A]-Tat (48鈥?0); N-E5L-Tat (48鈥?0)
Sequence GLLEALAELLEGRKKRRQRRRPPQ
Sequence Length 24
UniProt ID D2DUQ8
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C123H220N46O33
Absent amino acids CDFHIMNSTVWY
Common amino acids R
Mass 328181
Pl 12.22
Basic residues 8
Acidic residues 3
Hydrophobic residues 7
Net charge 5
Boman Index -10203
Hydrophobicity -140.42
Aliphatic Index 89.58
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27713223
Title Fusion of a Short HA2-Derived Peptide Sequence to Cell-Penetrating Peptides Improves Cytosolic Uptake, but Enhances Cytotoxic Activity
Doi Not available
Year 2009
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12032