This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-PS1, Dermaseptin cDNA
General Information
DRACP ID DRACP03738
Peptide Name Dermaseptin-PS1, Dermaseptin cDNA
Sequence ALWKTMLKKLGTVALHAGKAALGAVADTISQ
Sequence Length 31
UniProt ID A0A284T6N8
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C143H243N39O39S
Absent amino acids CEFNPRY
Common amino acids A
Mass 370014
Pl 10.8
Basic residues 5
Acidic residues 1
Hydrophobic residues 16
Net charge 4
Boman Index 554
Hydrophobicity 50.32
Aliphatic Index 116.77
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 183.33
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30461197
Title Novel peptide dermaseptin-PS1 exhibits anticancer activity via induction of intrinsic apoptosis signalling
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12112
This work is licensed under a Creative Commons Attribution 4.0 International License.