PKIL+L39e (4-18)[P6I,K10I], PaDBS1R1

General Information


DRACP ID  DRACP03739

Peptide Name   PKIL+L39e (4-18)[P6I,K10I], PaDBS1R1

Sequence  PKILNKILGKILRLAAAFK

Sequence Length  19

UniProt ID  Q8ZTX6 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C101H179N27O21

Absent amino acids  CDEHMQSTVWY

Common amino acids  KL

Mass  242897

Pl  12

Basic residues  5

Acidic residues  0

Hydrophobic residues  11

Net charge  5

Boman Index  3

Hydrophobicity  59.47

Aliphatic Index  159.47

Half Life 
  Mammalian: 4.4 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30463701

Title  Fast and potent bactericidal membrane lytic activity of PaDBS1R1, a novel cationic antimicrobial peptide

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12113

DRACP is developed by Dr.Zheng's team.