Arminin-1a (40-70)-AMD

General Information


DRACP ID  DRACP03743

Peptide Name   Arminin-1a (40-70)-AMD

Sequence  KPWRFRRAIRRVRWRKVAPYIPFVVKTVGKK

Sequence Length  31

UniProt ID  D2XUU4 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C185H301N59O34

Absent amino acids  CDEHLMNQS

Common amino acids  R

Mass  443105

Pl  12.91

Basic residues  12

Acidic residues  0

Hydrophobic residues  13

Net charge  12

Boman Index  -8968

Hydrophobicity  -67.1

Aliphatic Index  78.39

Half Life 
  Mammalian: 4.4 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  12490

Absorbance 280nm  416.33

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30464401

Title  Arminin 1a-C, a novel antimicrobial peptide from ancient metazoan Hydra, shows potent antileukemia activity against drug-sensitive and drug-resistant leukemia cells

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12161

DRACP is developed by Dr.Zheng's team.